Lifetime Estrogen Exposure Associated with Better Cognitive Performance in Women

A new study published in the Journal of Alzheimer’s Disease suggests that women who experience greater lifetime exposure to estrogen may exhibit better cognitive performance and maintain larger brain volumes as they age. The research indicates that factors such as a later age of menopause, a higher number of live births, and the use of hormone replacement therapy are linked to indicators of better brain health. These findings add to a growing body of evidence attempting to explain the biological underpinnings of sex differences in neurodegenerative diseases.