Light-Stimulated Graphene Activates and Matures Neurons

By using light to stimulate neurons, scientists can gain spatiotemporal control over neural activity. But neurons naturally respond to electrical signals—not light—so researchers typically manipulate them either genetically or structurally. Concerned about the effects of these changes, biophysicists sought a more natural way to stimulate neurons in cell culture. In a recent study, the researchers grew neurons on a coverslip coated with graphene, a thin layer of carbon atoms, and showed that these cells acquired sensitivity to light.. They also found that graphene could promote the maturation of neurons in 3D human brain organoids with no noticeable signs of toxicity.