Scientists Discover “Molecular Switch” That Fuels Alzheimer’s Brain Inflammation

The brain has its own built-in immune system that identifies threats and responds to them. In Alzheimer’s disease, growing evidence shows that this system becomes persistently overactive. The result is chronic inflammation that damages the connections between brain cells. In a preclinical study using human Alzheimer’s brain cells, scientists at Scripps Research have identified a molecular trigger behind this process. The finding points to a potential drug target that could help control harmful inflammation.